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. Author manuscript; available in PMC: 2015 Dec 20.
Published in final edited form as: Stat Med. 2014 Sep 28;33(29):5097–5110. doi: 10.1002/sim.6310

Figure 1.

Figure 1

Flow chart of the two-stage adaptive cutoff (TACO) procedure. θ0 denote a pre-specified error rate below which a model would be deemed acceptable. The significance levels α2 and α2 are chosen so that (α1 × α2) does not exceed some pre-specified type I error α (e.g. 0.05).