Table 4.
Findings of GEI with significant meta-analysis p-values for the single-nucleotide polymorphisms (SNPs) that have demonstrated significant and replicated evidence of marginal association with BMI in the MESA data (adjusted α = 1.9 × 10−3).
| Exposure | SNP ID | Gene | Tukey LRT | Shrinkage Wald | Saturated LRT |
|---|---|---|---|---|---|
| Energy Intake | rs543874 | SEC16B | <1.0 × 10−8 | <1.0 × 10−8 | 1.8×10−4 |
| rs1558902 | FTO | 4.8 × 10−5 | 7.4 × 10−4 | 0.130 | |
| rs10767664 | BDNF | 1.2 × 10−3 | 0.103 | 0.124 | |
|
| |||||
| Exercise | rs206936 | NUDT3, HMGA1 | 1.4 × 10−4 | 0.006 | 0.005 |