Table 3. Potential epigenetic therapeutic targets of ɣ-globin gene silencing.
DNA methyl transferases |
Histone deacetylases |
Histone demethylases |
Methyl-CpG binding domain protein 2 (MBD2) |
Mi2p/CHD4 ATPase chromatin remodeler |
PRMT5 |
Friend of PRMT1 (FoP) |