Table 1.

Characteristics of patients with irinotecan-based HIPEC

Patient	Previous syst. CTx	Previous syst. OX	Recurrent PM	Rationale for irinotecan-based HIPEC
Patient 1	yes	yes	yes	Oxaliplatin-associated peripheral neuropathy
Patient 2	yes	yes	no	2ndline irinotecan-based systemic chemothera-py after disease progression
Patient 3	yes	no	no	Systemic irinotecan-based chemotherapy with response
Patient 4	yes	yes	no	Systemic irinotecan-based chemotherapy with response
Patient 5	yes	no	no	Systemic irinotecan-based chemotherapy with response
Patient 6	yes	no	no	Systemic irinotecan-based chemotherapy with response
Patient 7	yes	no	no	Systemic irinotecan-based chemotherapy with response
Patient 8	yes	yes	no	Oxaliplatin-associated peripheral neuropathy
Patient 9	yes	no	no	Systemic irinotecan-based chemotherapy with response
Patient 10	yes	yes	no	Progressive disease under oxaliplatin-based systemic chemotherapy
Patient 11	yes	yes	yes	Progressive disease under oxaliplatin-based systemic chemotherapy
Patient 12	yes	no	no	Systemic irinotecan-based chemotherapy with response

CTx = chemotherapy; PM = peritoneal metastasis.