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Schematic diagram of the probable effect of GDF11 on the marker genes used and their respective expression patterns. Anterior is towards the top (adapted from Reichert H, 2002 [32]). Expression domains are colour coded: the expression domain of Bf1 is shown in the colour light blue, Otx1 domain in purple, Pax6 domain in orange, En1 domain in green, Gbx2 domain in red, Krox20 domain in dark blue and Hoxc9 in yellow, respectively.
