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. 2014 Nov 3;6(10):93. doi: 10.1186/s13073-014-0093-3

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© Hanses et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Number of genes differentially expressed in endocardial vegetations from (A) nondiabetic and (B) diabetic rats. Absolute number of genes down- (left) or upregulated (right) in endocardial vegetations compared with in vitro exponential (red bars), stationary (blue bars), or both growth phases (black bars). The four groups with the highest number of genes more highly expressed in vivo were amino acid transport and metabolism; carbohydrate transport and metabolism; virulence or immune evasion; and transcription, translation, and posttranslational modification.