Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Nov 3;6(10):93. doi: 10.1186/s13073-014-0093-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Hanses et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Comparative virulence of strain Newman and its isogenic sbnE deletion mutant. (A) Compared to rats infected with strain Newman, rats infected with the sbnE mutant (defective in the synthesis of the siderophore staphyloferrin B lived significantly longer than rats infected with the parental strain, (B) had significantly lower levels of bacteremia on day 2, and (C) lost significantly less weight 48 h after bacterial inoculation. (D) Bacterial burdens in the kidneys and (E) vegetations were not significantly different between wild-type and mutant strain.