Table 1.
List of selected genes differentially expressed in diabetic and nondiabetic vegetations
| Gene | Diabetic versus nondiabetic | Gene product | Functional group |
|---|---|---|---|
| acpS | 2.6 | holo-(acyl-carrier-protein) synthase | Lipid transport and metabolism |
| alr | 2.9 | alanine racemase | Cell wall/membrane biogenesis |
| argG | 10.0 | argininosuccinate synthase | Amino acid transport and metabolism |
| argH | 15.3 | argininosuccinate lyase | Amino acid transport and metabolism |
| atpA | 3.8 | ATP synthase F1, alpha subunit | Energy production and conversion |
| atpE | 2.4 | ATP synthase F0, C subunit | Energy production and conversion |
| atpH | 3.3 | ATP synthase F1, delta subunit | Energy production and conversion |
| cap5F | 2.5 | capsular polysaccharide biosynthesis | Cell wall/membrane biogenesis |
| cap5K | 3.5 | capsular polysaccharide biosynthesis | Cell wall/membrane biogenesis |
| ccrB | 2.0 | cassette chromosome recombinase B | |
| dnaE | 2.6 | DNA polymerase III, alpha subunit | Nucleotide metabolism, replication, recombination |
| fabD | 3.3 | malonyl CoA-acyl carrier protein transacylase | Lipid transport and metabolism |
| gapA | 4.4 | glyceraldehyde 3-P dehydrogenase | Carbohydrate transport and metabolism |
| geh | 2.3 | glycerol ester hydrolase | Miscellaneous |
| glpP | 2.2 | glycerol uptake operon regulatory protein | Transcription, translation and post-translational modification |
| glyS | 4.2 | glycyl-tRNA synthetase | Transcription, translation and post-translational modification |
| hemX | 2.2 | hemX protein | Transcription, translation and post-translational mod. |
| infB | 2.6 | translation initiation factor IF-2 | Transcription, translation and post-translational modification |
| kdpE | 2.4 | DNA-binding response regulator | Regulatory |
| ligA | 2.3 | DNA ligase, NAD-dependent | Nucleotide metabolism, replication, recombination |
| menD | 2.1 | carboxylic acid synthase | Coenzyme transport and metabolism |
| moeA | 3.4 | molybdopterin biosynthesis, putative | Coenzyme transport and metabolism |
| nrdF | 2.7 | ribonucleoside-diphosphate reductase 2 | Nucleotide metabolism, replication, recombination |
| pls | 3.7 | plasmin-sensitive protein | Virulence |
| recQ | 2.8 | ATP-dependent DNA helicase | Nucleotide metabolism, replication, recombination |
| rexA | 3.2 | exonuclease | Nucleotide metabolism, replication, recombination |
| ribD | 2.7 | riboflavin biosynthesis protein | Coenzyme transport and metabolism |
| ribE | 2.4 | riboflavin synthase, alpha subunit | Coenzyme transport and metabolism |
| ruvB | 2.2 | Holliday junction DNA helicase | Nucleotide metabolism, replication, recombination |
| sasA | 4.8 | LPXTG cell wall surface protein | Virulence |
| sirC | 3.1 | iron ABC transporter, permease protein | Inorganic ion transport and metabolism |
| ureC | 7.5 | urease, alpha subunit | Amino acid transport and metabolism |