Table 1.
A summary of specific language impairment (SLI) linkage in OMIM
| Region | Cytogenetic loci | Associated gene(s) | OMIM no. | Method | References |
|---|---|---|---|---|---|
| SLI1 | 16q23.1–16q24 | CMIP; ATP2C2 | 606711 | GWLA, targeted association | [4, 5, 10] |
| SLI2 | 19q13.13–19q13.41 | N/A | 606712 | GWLA | [4, 5] |
| SLI3 | 13q14.3–13q31.1 | N/A | 607134 | GWLA | [6, 7] |
| SLI4 | 7q31–7q36 | CNTNAP2 | 612514 | GWLA, targeted association | [4, 5, 9] |
| SLI5 | 2q36 | TM4SF20 | 615432 | LA | [25•] |
ATP2C2 calcium-transporting ATPase type 2C, CMIP c-maf-inducing protein, CNTNAP2 contactin associated protein-like 2, GWLA genome-wide linkage analysis, LA linkage analysis, N/A not applicable, TM4SF20 transmembrane 4 L six family member 20