Table 2.

Acute-toxicity of Ma Zi Ren Wan (MZRW)

			Dosage g/kg
	75	37.5	19.25	9.625	4.8125
Before administered drug	22.2 ± 1.1	20.4 ± 0.6	21.1 ± 1.6	21.8 ± 1.7	23.3 ± 1.9
After administered drug	28.7 ± 4.1	25.5 ± 3.0	25.5 ± 1.1	26.1 ± 1.1	30.3 ± 1.6

Sixty ICR mice, which were divided into five groups, were used in the acute-toxic test. The mice weighed 18 to 22 g. The drug was dissolved with distilled water and administered 20 ml/kg orally. The details about dosage were as follows: 75 g/kg, 37.5 g/kg, 19.25 g/kg, 9.625 g/kg, and 4.8125 g/kg. The dosages equaled 300, 150, 75, 37.5, and 19.75 times of clinical dosage. Untoward reaction did not be observed after mice were administered the drug. Administered drug 7 days later, no one died. The weight of mice was listed as Table 2.