Table 3.
Associations between number of vertebral fracture and lung function
| |
Pulmonary function (mean (SD) or (SE)) |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |
Men |
Women |
||||||||||
| |
Number of vertebral fractures |
Number of vertebral fractures |
||||||||||
| 0 (n=771) | 1 (n=83) | 2 (n=26) | 3 (n=9) | 4-6 (n=3) | P trend | 0 (n=1079) | 1 (n=103) | 2 (n=37) | 3 (n=11) | 4-6 (n=10) | P trend | |
| FVC% predicteda |
98.2 (15.3) |
97.9 (17.9) |
99.5 (17.1) |
90.0 (15.2) |
80.1 (10.3) |
0.047 |
101.2 (15.8) |
102.6 (18.3) |
101.7 (17.4) |
107.6 (16.1) |
94.1 (21.1) |
0.137 |
| FEV1% predicteda |
88.9 (16.9) |
87.2 (20.2) |
84.3 (24.9) |
79.6 (22.7) |
70.8 (12.3) |
0.007 |
93.0 (17.4) |
94.2 (20.5) |
93.1 (20.5) |
94.2 (24.0) |
83.9 (23.3) |
0.437 |
| FEV1/FVC% predicteda |
90.6 (10.8) |
88.8 (10.9) |
83.2 (17.7) |
87.2 (16.4) |
87.8 (4.3) |
0.002 |
92.0 (9.1) |
91.2 (10.4) |
91.1 (9.3) |
86.0 (13.7) |
88.0 (10.5) |
0.021 |
| Adjustedb values |
(n=665) |
(n=74) |
(n=22) |
(n=7) |
(n=2) |
|
(n=800) |
(n=65) |
(n=26) |
(n=5) |
(n=8) |
|
| FVC (liter (SE)) |
4.22 (0.024) |
4.22 (0.073) |
4.29 (0.133) |
4.18 (0.237) |
4.10 (0.442) |
0.982 |
2.99 (0.015) |
3.09 (0.053) |
2.90 (0.084) |
2.89 (0.192) |
2.75 (0.154) |
0.321 |
| FEV1 (liter (SE)) |
3.08 (0.021) |
3.07 (0.063) |
2.94 (0.116) |
3.24 (0.206) |
3.12 (0.384) |
0.747 |
2.21 (0.013) |
2.32 (0.046) |
2.15 (0.073) |
2.04 (0.166) |
2.08 (0.134) |
0.476 |
| FEV1/FVC (SE) | 0.73 (0.003) | 0.73 (0.009) | 0.67 (0.016) | 0.79 (0.028) | 0.76 (0.053) | 0.502 | 0.74 (0.002) | 0.75 (0.008) | 0.74 (0.013) | 0.69 (0.029) | 0.76 (0.023) | 0.874 |
The Tromsø Study 2007-08.
aEquation from Langhammer et al. [27].
bAdjusted for age, smoking habits, height, weight, physical inactivity, cardiovascular disease, lung disease, corticosteroids, hip BMD, hormones for menopause (women).