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. 2014 Oct 29;2014:741470. doi: 10.1155/2014/741470

Table 1.

Hematological values of control group and rats treated with C. papaya leaf extract measured during the subchronic toxicity study.

Male rats Control 0.01 g/kg BW 0.14 g/kg BW 2 g/kg BW
WBC (10³/μL) 4.74 ± 2.04 6.01 ± 2.84 3.69 ± 1.55 6.24 ± 2.73
RBC (106×μL) 7.89 ± 0.42 7.96 ± 0.40 7.88 ± 0.51 8.03 ± 0.37
HGB (g/dL) 16.30 ± 0.49 16.13 ± 0.72 16.27 ± 0.81 16.34 ± 0.73
HCT (%) 40.08 ± 1.42 39.83 ± 1.97 40.11 ± 1.87 39.97 ± 1.86
MCV (fL) 50.84 ± 1.69 49.98 ± 1.32 50.94 ± 1.74 49.79 ± 1.55
MCH (pg) 20.69 ± 0.74 20.24 ± 0.53 20.67 ± 0.54 20.38 ± 0.56
MCHC (g/dL) 40.70 ± 0.50 40.51 ± 0.42 40.58 ± 0.49 40.93 ± 0.50
PLT (10³/μL) 637.67 ± 100.04 697.88 ± 69.91 563.44 ± 209.03 718.67 ± 111.74

Female rats Control 0.01 g/kg BW 0.14 g/kg BW 2 g/kg BW

WBC (10³/μL) 2.13 ± 0.98 1.71 ± 0.97 1.65 ± 1.25 3.40 ± 2.41
RBC (106×μL) 7.22 ± 0.45 7.05 ± 0.21 6.89 ± 0.51 6.85 ± 0.68
HGB (g/dL) 15.57 ± 0.79 15.16 ± 0.38 14.61 ± 1.09 14.38 ± 1.29
HCT (%) 37.57 ± 1.97 36.55 ± 0.98 35.45 ± 2.83 34.70 ± 3.29
MCV (fL) 52.08 ± 1.59 51.87 ± 0.97 51.45 ± 1.04 50.70 ± 1.81
MCH (pg) 21.59 ± 0.72 21.52 ± 0.46 21.23 ± 0.42 21.04 ± 0.67
MCHC (g/dL) 41.47 ± 0.62 41.49 ± 0.48 41.29 ± 0.60 41.54 ± 0.45
PLT (10³/μL) 708.40 ± 117.74 681.70 ± 56.09 464.50 ± 272.37 535.00 ± 290.60

Values are expressed as mean ± standard deviation (n = 10/group). WBC: white blood cells, RBC: red blood cells, HGB: Hemoglobin, HCT: hematocrit, MCV: mean corpuscular volume, MCH: mean cell hemoglobin, MCHC: mean corpuscular hemoglobin concentration, and PLT: platelet. P value less than 0.05 (P < 0.05), significant value.