RF hyperthermia treatment of mouse cholangiocarcinoma and swine CBD. A, A 0.022-inch RF hyperthermia wire (open arrow) is placed in the center of the tumor, which is connected to the RF generator by a cable (solid arrow), while a fiberoptic temperature probe (arrowhead) is percutaneously placed at the margin of the tumor to instantly measure the temperature. B, X-ray fluoroscopic image shows the 10-F introducer (arrow) placed in the CBD of a pig. C, An RF hyperthermia wire (arrow) was positioned within a microporous agent delivery balloon (arrowheads = the two markers of the balloon).