Table 3.

Statistical analysis of variation in non-susceptibility between cohorts and over time among 108 717 clinical isolates from primary, secondary and tertiary care patients in West London, 2009–13

	Between hospital critical care: Hospital 1 versus Hospital 2		Between hospital wards: Hospital 1 versus Hospital 2		Within Hospital 1: critical care versus wards		Within Hospital 2: critical care versus wards		Renal: inpatients versus outpatients
Enterobacteriaceae, ESBL/AmpC phenotype	2009–10	*	2009–10	NS	2009–10	***	2009–10	***	2009–10	**
	2010–11	***	2010–11	NS	2010–11	NS	2010–11	***	2010–11	***
	2011–12	NS	2011–12	***	2011–12	***	2011–12	***	2011–12	***
	2012–13	*	2012–13	**	2012–13	***	2012–13	***	2012–13	***
Enterobacteriaceae, ciprofloxacin non-susceptible	2009–10	NS	2009–10	*	2009–10	NS	2009–10	NS	2009–10	***
	2010–11	*	2010–11	*	2010–11	**	2010–11	NS	2010–11	***
	2011–12	NS	2011–12	**	2011–12	*	2011–12	NS	2011–12	***
	2012–13	NS	2012–13	*	2012–13	NS	2012–13	NS	2012–13	***
Pseudomonas spp., ciprofloxacin non-susceptible	2009–10	NS	2009–10	NS	2009–10	*	2009–10	*	2009–10	*
	2010–11	NS	2010–11	***	2010–11	NS	2010–11	*	2010–11	***
	2011–12	NS	2011–12	NS	2011–12	**	2011–12	***	2011–12	*
	2012–13	*	2012–13	*	2012–13	NS	2012–13	***	2012–13	NS
Pseudomonas spp., piperacillin/tazobactam non-susceptible	2009–10	***	2009–10	NS	2009–10	NS	2009–10	***	2009–10	***
	2010–11	NS	2010–11	*	2010–11	***	2010–11	***	2010–11	***
	2011–12	NS	2011–12	NS	2011–12	NS	2011–12	***	2011–12	NS
	2012–13	NS	2012–13	*	2012–13	NS	2012–13	***	2012–13	NS
Pseudomonas spp., meropenem non-susceptible	2009–10	NS	2009–10	NS	2009–10	***	2009–10	***	2009–10	***
	2010–11	***	2010–11	**	2010–11	***	2010–11	***	2010–11	***
	2011–12	*	2011–12	NS	2011–12	***	2011–12	***	2011–12	NS
	2012–13	*	2012–13	*	2012–13	***	2012–13	***	2012–13	**
Enterococcus spp., glycopeptide non-susceptible	2009–10	*	2009–10	***	2009–10	***	2009–10	***	2009–10	***
	2010–11	NS	2010–11	**	2010–11	***	2010–11	***	2010–11	***
	2011–12	NS	2011–12	**	2011–12	**	2011–12	***	2011–12	***
	2012–13	NS	2012–13	**	2012–13	***	2012–13	*	2012–13	***
Enterococcus spp., amoxicillin non-susceptible	2009–10	NS	2009–10	***	2009–10	**	2009–10	***	2009–10	***
	2010–11	NS	2010–11	***	2010–11	**	2010–11	***	2010–11	***
	2011–12	NS	2011–12	***	2011–12	***	2011–12	***	2011–12	***
	2012–13	**	2012–13	***	2012–13	***	2012–13	**	2012–13	***
S. aureus, methicillin non-susceptible	2009–10	***	2009–10	***	2009–10	*	2009–10	NS	2009–10	*
	2010–11	NS	2010–11	***	2010–11	NS	2010–11	**	2010–11	*
	2011–12	**	2011–12	*	2011–12	NS	2011–12	***	2011–12	NS
	2012–13	NS	2012–13	NS	2012–13	NS	2012–13	NS	2012–13	*

NS, no significant difference.

*Significant at P < 0.05.

**Significant at P < 0.01.

***Significant at P < 0.001.