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. 2014 Nov 12;5:564. doi: 10.3389/fimmu.2014.00564

Table 2.

Multivariable GEE analysis of milk ELISA as a continuous (S/P % ELISA readings) and categorical (milk ELISA MAP positive/negative) dependent variable and independent variables.

Continuous variable
(S/P % ELISA readings)
Categorical variable
(Milk ELISA MAP positive/negative)

Dependent variable
Milk ELISA
Coefficient P Value significant:
P < 0.05
95% C.I. Odds ratio P value 95% C.I. Model
(P value <0.001)

Independent variable
Time point
June 20 vs. Maya 17.2 <0.001 14.3, 20.2 11.1 <0.001 5.8, 21.0
July 11 vs. May 5.43 <0.001 2.5, 8.4 2.7 0.004 1.4, 5.1
July 24 vs. May 0.29 0.850 −2.7, 3.3 1.1 0.819 0.5, 2.3
August 8 vs. May 0.94 0.537 −2.1, 3.9 1.1 0.831 0.5, 2.3 Sampling time point
August 21 vs. May 0.42 0.784 −2.6, 3.4 1.1 0.829 0.5, 2.3 Parity
Oct vs. May 1.51 0.322 −1.5, 4.5 1.8 0.105 0.9, 3.5 Breed
Nov vs. May 5.65 <0.001 2.6, 8.7 2.5 0.007 1.3, 4.9 Calving date
Parity
1b vs. 2 −11.2 <0.001 −5.4, −17.0 0.3 0.004 1.6, 10.3
2 vs. 3 11.2 0.001 17.5, 4.7 3.3 0.025 0.1, 0.9
2 vs. 4 8.3 0.002 13.5, 3.1 2.5 0.014 0.2, 0.8

aMay is the ELISA sample taken pre SICCT. bParity 1: 1st lactation. No significant interactions identified with other independent variables. C.I., confidence interval. Coefficient, difference across the sample population. Statistically significant P values highlighted in bold.