Table 1.
Baseline characteristics at enrollment
| AL (N = 360) | AA (N = 387) | All (N = 747) | P value | |
|---|---|---|---|---|
| Male gender n (%) | 201(56) | 213(56) | 414(56) | 0.95 |
| Mean Age (months) (SD) | 36.1(17.2) | 36.6 (15.2) | 36.3 (16.2) | 0.83 |
| Number aged < 1 year | 28 (7.8%) | 17 (4.4%) | 45 (6.1%) | 0.04 |
| Duration of illness (days) | ||||
| Mean (SD) | 2.9 (0.9) | 3.0(1.3) | 3.0(1.1) | 0.39 |
| Range | 1–6 | 1–7 | 1–7 | |
| Weight [Kg] | ||||
| Mean (SD) | 13.2 (4.5) | 13.5 (4.0) | 13.3 (4.3) | 0.17 |
| Range | 5.5–24 | 5.5–24 | 5.5–24 | |
| Body temperature (°C) | ||||
| Mean (SD) | 38.0 (1.1) | 38.0 (1.1) | 38.0 (1.1) | 0.71 |
| Range | 35.7–40.5 | 35.2–40.4 | 35.2 40.5 | |
| No. with temperature P > 37.4 (°C) [%] | 267[74.2] | 291 [75.2] | 558[74.7] | 0.81 |
| No. with temperature > 40 (°C) | 13 (3.6) | 12 (3.1) | 25 (3.3) | 0.85 |
| Hematocrit | ||||
| Mean (SD) | 29.4 (5.3) | 30.0 (5.7) | 29.7 (5.5) | 0.34 |
| Range | 17–42 | 15–43 | 15–43 | |
| No. with hematocrit < 30% | 68(N = 154) | 76(N = 169) | 144(N = 323) | 0.88 |
| Geometric mean parasitemia (/μL) and range | 15169 (1,290–200,000) | 14370 (1,100–200,000) | 14749 (1,100–200,000) | 0.60 |
| Number with gametocytaemia (%) | 82 (22.8) | 77 (19.9) | 159 (21) | 0.63 |
AL = artemether-lumefantrine; AA = artesunate-amodiaquine.
Liver was enlarged in 161 of 517 children (31.1%) and spleen in 135 of 517 children (26.1%), P = 0.07.