Table 2.
Efficacy of artemether-lumefantrine or amodiaquine-artesunate according to study site*
| Artemether-lumefantrine: | |||||||
|---|---|---|---|---|---|---|---|
| State | PCR uncorrected | PCR corrected | |||||
| ACPR_u | Failure_u | Total | ACPR_c | Recrudescence | Total | % Recrudescence | |
| Borno (Damboa) | 51 | 5 | 56 | 52 | 3 | 55 | 5.5 |
| Cross River (Ikot Ansa) | 26 | 1 | 27 | 27 | 0 | 27 | 0 |
| Enugu (Agbani) | 48 | 8 | 56 | 50 | 6 | 56 | 10.7 |
| Kaduna (Makarfi) | 55 | 1 | 56 | 55 | 1 | 56 | 1.8 |
| Lagos (Ijede) | 43 | 4 | 47 | 45 | 0 | 45 | − |
| Oyo (Ibadan) | 47 | 1 | 48 | 47 | 1 | 48 | 2.1 |
| Plateau (Barkin Ladi) | 41 | 11 | 52 | 43 | 6 | 49 | 12.2 |
| Total | 311 | 31 | 342 | 319 | 17 | 336 | 5.1 |
| Amodiaquine-artesunate: | |||||||
| State | PCR uncorrected | PCR corrected | |||||
| ACPR_u | Failure_u | Total | ACPR_c | Recrudescence | Total | % Recrudescence | |
| Borno (Damboa) | 58 | 2 | 60 | 60 | 0 | 60 | − |
| Cross River (Ikot Ansa) | 33 | 1 | 34 | 34 | 0 | 34 | − |
| Enugu (Agbani) | 44 | 8 | 52 | 44 | 7 | 51 | 13.7 |
| Kaduna (Makarfi) | 59 | 0 | 59 | 59 | 0 | 59 | − |
| Lagos (Ijede) | 48 | 2 | 50 | 48 | 2 | 50 | 4.0 |
| Oyo (Ibadan) | 52 | 4 | 56 | 52 | 4 | 56 | 7.1 |
| Plateau (Barkin Ladi) | 48 | 11 | 59 | 51 | 4 | 55 | 7.3 |
| Total | 342 | 28 | 370 | 348 | 17 | 365 | 4.7 |
*
ACPR u = adequate clinical and parasitological response uncorrected. ACPR c = adequate clinical and parasitological response corrected. Failure u = treatment failure uncorrected; PCR = polymerase chain reaction.