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. Author manuscript; available in PMC: 2014 Nov 12.
Published in final edited form as: Circ J. 2012 Oct 6;77(2):323–329. doi: 10.1253/circj.cj-12-0886

Table 3.

Hazard Ratio (HR) and 95% Confidence Intervals (CI) of Atrial Fibrillation by Dietary Magnesium Quintile, Atherosclerosis Risk in Communities, 1987 to 2009

Dietary Magnesium (mg/day)
P for Trend*
<180.90 (n=2711) 180.90–223.16 (n=2711) 223.17–264.76 (n=2712) 264.77–320.08 (n=2711) ≥320.08 (n=2711)
Cases 295 335 315 343 359
Person-years 49,579 49,852 50,303 50,474 48,473
Crude Incidence Rate (per 1000 person-years) 5.95 6.72 6.26 6.80 7.41
Model 1 HR (95% CI) 1.09 (0.92–1.30) 1.10 (0.94–1.28) 1.00 (Reference) 1.03 (0.88–1.20) 1.05 (0.88–1.26) 0.51
Model 2 HR (95% CI) 1.07 (0.88–1.31) 1.10 (0.93–1.29) 1.00 (Reference) 1.05 (0.89–1.24) 1.09 (0.87–1.37) 0.80
Model 3 HR (95% CI) 1.10 (0.91–1.34) 1.12 (0.95–1.32) 1.00 (Reference) 1.04 (0.88–1.23) 1.07 (0.86–1.35) 0.55
Model 4 HR (95% CI) 1.02 (0.83–1.24) 1.04 (0.89–1.23) 1.00 (Reference) 1.05 (0.89–1.24) 1.09 (0.86–1.36) 0.82

Model 1: Cox proportional hazards model adjusted for age, sex, race, study site, and total energy intake.

Model 2: Model 1 with additional adjustment for body mass index, high density lipoprotein cholesterol, low density lipoprotein cholesterol, smoking status, drinking status, educational level, systolic blood pressure, diabetes, antihypertensive medication, and intake of potassium, calcium, dietary fiber, protein, caffeine, and polyunsaturated to saturated fat ratio.

Model 3: Model 2 with additional adjustment for prevalent myocardial infarction, heart failure, or stroke at baseline.

Model 4: Model 3 with additional adjustment for incident myocardial infarction, heart failure, or stroke as time-varying covariates.

*

Linear trend in quintile number.