Table 3.
Dietary Magnesium (mg/day)
|
P for Trend* | |||||
---|---|---|---|---|---|---|
<180.90 (n=2711) | 180.90–223.16 (n=2711) | 223.17–264.76 (n=2712) | 264.77–320.08 (n=2711) | ≥320.08 (n=2711) | ||
Cases | 295 | 335 | 315 | 343 | 359 | |
Person-years | 49,579 | 49,852 | 50,303 | 50,474 | 48,473 | |
Crude Incidence Rate (per 1000 person-years) | 5.95 | 6.72 | 6.26 | 6.80 | 7.41 | |
Model 1 HR (95% CI) | 1.09 (0.92–1.30) | 1.10 (0.94–1.28) | 1.00 (Reference) | 1.03 (0.88–1.20) | 1.05 (0.88–1.26) | 0.51 |
Model 2 HR (95% CI) | 1.07 (0.88–1.31) | 1.10 (0.93–1.29) | 1.00 (Reference) | 1.05 (0.89–1.24) | 1.09 (0.87–1.37) | 0.80 |
Model 3 HR (95% CI) | 1.10 (0.91–1.34) | 1.12 (0.95–1.32) | 1.00 (Reference) | 1.04 (0.88–1.23) | 1.07 (0.86–1.35) | 0.55 |
Model 4 HR (95% CI) | 1.02 (0.83–1.24) | 1.04 (0.89–1.23) | 1.00 (Reference) | 1.05 (0.89–1.24) | 1.09 (0.86–1.36) | 0.82 |
Model 1: Cox proportional hazards model adjusted for age, sex, race, study site, and total energy intake.
Model 2: Model 1 with additional adjustment for body mass index, high density lipoprotein cholesterol, low density lipoprotein cholesterol, smoking status, drinking status, educational level, systolic blood pressure, diabetes, antihypertensive medication, and intake of potassium, calcium, dietary fiber, protein, caffeine, and polyunsaturated to saturated fat ratio.
Model 3: Model 2 with additional adjustment for prevalent myocardial infarction, heart failure, or stroke at baseline.
Model 4: Model 3 with additional adjustment for incident myocardial infarction, heart failure, or stroke as time-varying covariates.
Linear trend in quintile number.