Table 1.

Expression of common genes in the livers of rats treated with folic acid, tributyrin, or a combination of folic acid and tributyrin (p<0.05).

#	Gene name	Gene bank ACC#	Description	Fold change
				Folic acid	Tributyrin	Folic acid +tributyrin
1	Sctra,b	NM_031115	Secretin receptor	−5.65	−3.55	−4.00
2	Wisp2b	NM_031590	WNT1 inducible signaling pathway protein 2	−4.67	−3.91	−4.40
3	Lpl	NM_012598	Lipoprotein lipase	−4.27	−2.62	−3.96
4	Rgnefa	NM_001108542	Rho-guanine nucleotide exchange factor	−4.06	−2.70	−4.05
5	Ly49i6	NM_001009718	Ly49 inhibitory receptor 6	−3.72	−3.27	−2.65
6	Fabp4b	NM_053365	Fatty acid binding protein 4, adipocyte	−3.69	−3.06	−2.27
7	Ampd3	NM_031544	Adenosine monophosphate deaminase 3	−3.68	−3.44	−3.47
8	Ccl2a	NM_031530	Chemokine (C-C motif) ligand 2	−3.53	−4.01	−4.59
9	Lrrcc1	NM_001100645	Leucine rich repeat and coiled-coil domain containing 1	−3.51	−2.98	−4.41
10	Mgpa	NM_012862	Matrix Gla protein	−3.50	−2.45	−3.33
11	Klf5b	NM_053394	Kruppel-like factor 5	−3.45	−2.77	−4.30
12	Efs	NM_001106033	Embryonal Fyn-associated substrate	−3.32	−2.74	−3.61
13	Itgb6a	NM_001004263	Integrin, beta 6	−3.26	−3.12	−4.02
14	Spdef	NM_001109530	SAM pointed domain containing ets transcription factor	−3.24	−3.14	−3.52
15	Rab25a	NM_001107687	RAB25, member RAS oncogene family	−3.07	−2.77	−3.14
16	Tmeff2	NM_001108795	Transmembrane protein with EGF-like and two follistatin-like domains 2	−3.03	−3.01	−4.15
17	Smoc2a	NM_001106215	SPARC related modular calcium binding 2	−3.02	−3.65	−4.72
18	Gcnt3	NM_173312	Glucosaminyl (N-acetyl) transferase 3, mucin type	−2.91	−5.35	−8.47
19	Tlr11	NM_001144779	Toll-like receptor 11	−2.87	−3.82	−4.81
20	Anxa8a	NM_001031654	Annexin A8	−2.87	−2.15	−2.39
21	Ccdc8	NM_001009533	Coiled-coil domain containing 8	−2.87	−2.77	−3.81
22	Slpi	NM_053372	Secretory leukocyte peptidase inhibitor	−2.79	−2.02	−2.30
23	Clec9a	NM_001109354	C-type lectin domain family 9, member A	−2.78	−2.17	−2.63
24	Tns4a	NM_001024881	Tensin 4	−2.75	−2.46	−4.31
25	Edn1a,b	NM_012548	Endothelin 1	−2.73	−3.20	−3.75
26	Stk39	NM_019362	Serine threonine kinase 39	−2.65	−2.34	−1.69
27	Slco3a1	NM_177481	Solute carrier organic anion transporter family, member 3a1	−2.64	−1.84	−2.39
28	Flt3a	NM_001100822	Fms-related tyrosine kinase 3	−2.57	−2.01	−2.35
29	Map3k6a,b	NM_001107909	Mitogen-activated protein kinase kinase kinase 6	−2.57	−2.11	−2.25
30	Pacrg	NM_001077677	Park2 co-regulated	−2.55	−2.03	−2.75
31	Arhgap22a	NM_001107297	Rho gtpase activating protein 22	−2.51	−2.75	−3.18
32	Kitlga,b	NM_021843	KIT ligand (Kitlg), transcript variant 1	−2.49	−2.34	−3.00
33	Plxdc2	NM_001108422	Plexin domain containing 2	−2.48	−2.40	−2.34
34	Asb2	NM_001011984	Ankyrin repeat and SOCS box-containing 2	−2.41	−1.87	−2.11
35	Egr2b	NM_053633	Early growth response 2	−2.35	−2.40	−2.76
36	Mmp24a,b	NM_031757	Matrix metallopeptidase 24	−2.26	−1.82	−2.75
37	Bcl2l14	NM_001024338	Bcl2-like 14 (apoptosis facilitator)	−2.21	−2.60	−2.32
38	Cxcl2a	NM_053647	Chemokine (C-X-C motif) ligand 2	−2.18	−2.39	−4.02
39	St14	NM_053635	Suppression of tumorigenicity 14 (colon carcinoma)	−2.13	−1.98	−2.16
40	P2ry6	NM_057124	Pyrimidinergic receptor P2Y, G-protein coupled, 6	−2.12	−1.64	−2.42
41	Dctd	NM_001013882	Dcmp deaminase (Dctd), transcript variant 1	−2.12	−2.33	−2.50
42	Lrrn4cl	NM_001109579	LRRN4 C-terminal like	−2.12	−2.20	−2.53
43	Frzba,b	NM_001100527	Frizzled-related protein	−2.08	−1.92	−2.27
44	Gas6a	NM_057100	Growth arrest specific 6	−2.08	−1.72	−2.07
45	Pgfa	NM_053595	Placental growth factor	−2.01	−1.56	−1.94
46	Itgada	NM_031691	Integrin, alpha D	−1.98	−1.86	−1.78
47	Nexn	NM_139230	Nexilin (F actin binding protein)	−1.96	−1.92	−2.90
48	Synj2a	NM_032071	Synaptojanin 2	−1.92	−1.53	−2.13
49	Rgs10	NM_019337	Regulator of G-protein signaling 10	−1.90	−1.62	−1.81
50	Gorab	NM_001100563	Golgin, RAB6-interacting	−1.89	−2.97	−2.85
51	Lsp1	NM_001025420	Lymphocyte-specific protein 1	−1.87	−1.61	−1.80
52	Atp10a	NM_001141935	Atpase, class V, type 10A	−1.87	−1.97	−1.92
53	St6galnac2	NM_001031652	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	−1.85	−1.98	−2.53
54	Mrvi1	NM_001105210	Murine retrovirus integration site 1 homolog	−1.83	−1.61	−2.00
55	Pld2a,b	NM_033299	Phospholipase D2	−1.83	−1.94	−2.03
56	Fbxw17	NM_001082409	F-box and WD-40 domain protein 17	−1.80	−1.97	−2.33
57	Pfkp	NM_206847	Phosphofructokinase, platelet	−1.78	−1.52	−1.59
58	Gna15	NM_053542	Guanine nucleotide binding protein, alpha 15	−1.78	−2.54	−2.68
59	Col4a4	NM_001008332	Collagen, type IV, alpha 4	−1.75	−2.38	−1.58
60	Nap1l3	NM_133402	Nucleosome assembly protein 1-like 3	−1.74	−2.18	−2.49
61	Prkar2ba	NM_001030020	Protein kinase, camp dependent regulatory, type II beta	−1.73	−1.64	−2.00
62	Fktn	NM_001108667	Fukutin	−1.71	−2.06	−1.77
63	Enc1a,b	NM_001003401	Ectodermal-neural cortex 1	−1.68	−1.58	−1.55
64	Srca,b	NM_031977	V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog	−1.66	−1.75	−1.72
65	Glsa	NM_012569	Glutaminase	−1.66	−1.55	−1.52
66	Cd200a	NM_031518	Cd200 molecule	−1.65	−2.00	−2.35
67	Spats2l	NM_001014102	Spermatogenesis associated, serine-rich 2-like	−1.62	−1.70	−2.06
68	Fut4a	NM_022219	Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	−1.61	−1.82	−2.20
69	Spock2	NM_001108533	Sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2	−1.59	−1.76	−2.01
70	Nrp1a,b	NM_145098	Neuropilin 1	−1.59	−1.53	−1.64
71	Reep5	NM_001108888	Receptor accessory protein 5	−1.58	−1.68	−1.62
72	Ap1s2	NM_001127531	Adaptor-related protein complex 1, sigma 2 subunit	−1.51	−1.52	−1.68
73	Il4ra	NM_133380	Interleukin 4 receptor, alpha	1.51	1.91	1.90
74	Rtn4rl1	NM_181377	Reticulon 4 receptor-like 1	1.62	1.99	2.41
75	Skp2b	NM_001106416	S-phase kinase-associated protein 2 (p45)	1.73	1.83	2.66
76	Fzd5a,b	NM_173838	Frizzled family receptor 5	1.90	2.75	3.16
77	Per2	NM_031678	Period homolog 2	2.25	2.46	2.73

^a- genes related to cell proliferation and angiogenesis.

^b- genes related to WNT pathway.