. Author manuscript; available in PMC: 2015 Jan 15.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Dec 3;0:225–232. doi: 10.1016/j.jchromb.2013.11.054

Table 3. K₂ and K₃EDTA Plasma Equivalence and Dilution Accuracy.

DTG in Plasma Matrix
EDTA Equivalence	K₂EDTA				K₃EDTA

	Low	Mid	High		Low	Mid	High

	15	450	9000	theoretical conc.	15	450	9000
	14.10	412.67	8676.90	mean	15.83	460.87	9236.90
	1.02	22.75	59.93	SD	0.31	20.72	149.29
	7.2	5.5	0.7	%CV	1.9	4.5	1.6
	-6.0	-8.3	-3.6	%dev	5.6	2.4	2.6
	-9.2	-3.5	-3.3	%diff^*	9.0	3.5	3.3

Dilutions of Ultra High QC	K₂EDTA				K₃EDTA

	1/5 dil	1/10 dil	1/20 dil		1/5 dil	1/10 dil	1/20 dil

	6000	3000	1500	theoretical conc.	6000	3000	1500
	5477.57	3004.63	1459.60	mean	5615.77	2863.67	1457.73
	173.29	24.99	17.13	SD	184.31	58.19	45.08
	3.2	0.8	1.2	%CV	3.3	2.0	3.1
	-8.7	0.2	-2.7	%dev	-6.4	-4.5	-2.8

%difference as compared to matrix matched QCs, determined by the following equation: (mean unmatched – mean matched)/[((mean unmatched + mean matched)/2)*100].

Table 3. K2 and K3EDTA Plasma Equivalence and Dilution Accuracy.

Table 3. K₂ and K₃EDTA Plasma Equivalence and Dilution Accuracy.