Table 1. Pharmacokinetic Variables of Free DOX and DOX-Loaded PEG5k–Fmoc–FTS2 Micelles.
groups | T1/2 (h) | AUC0-inf (μg × h/mL) | Cmax (μg/mL) | CL (L/h/kg) | Vd (L/kg) |
---|---|---|---|---|---|
DOX | 1.74 | 3.43 | 3.59 | 2.91 | 7.34 |
PEG5k–Fmoc–FTS2/DOX | 11.60 | 64.80 | 25.84 | 0.15 | 2.58 |