Figure 7. NF-κB did not attenuate 5-FU-induced cell death.

(A), Sa3 cells were incubated with or without 5 mg/mL of 5-FU for 1 h and 3 h. The cells then stained with anti-p65 antibody and the localization of p65 was detected by florescence microscopy. (B), Cell viability of Sa3 cells incubated with 5 mg/mL of 5-FU for 24 h after a 30-min pre-incubation with NF-κB inhibitors, 5 µM BAY or 200 µM CAPE. Values are means ± S.E.M. (n = 4). **p<0.01 compared to the control group.