Figure 13. PV-M₁KO mice exhibit no locomotor deficits in the open field maze.

Representative track plots of a (A) WT, (B) heterozygous and (C) PV-M₁KO mouse during the first 5 min in the open field maze. (D) line crossings, (E) rearings, (F) speed and (G) time immobile over the course of 60 min, binned in 5 min averages ± s.e.m. for (black rectangles) WT (n = 12) and (red circles) homozygous PV-M₁KO (n = 13) mice. No significant difference between mouse lines was observed at any of the time intervals (P > 0.05, Mann–Whitney test). M₁KO, M₁ muscarinic acetylcholine receptor knockout; PV, parvalbumin; WT, wild-type.