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. 2014 Jun 27;592(Pt 16):3611–3624. doi: 10.1113/jphysiol.2013.266494

Figure 5. Sensitization resulting from acute inflammation of the plantar hind foot is unaffected by intrathecal yohimbine.

Figure 5

Acute complete Freund's adjuvant (CFA)-induced inflammation of the plantar hind foot resulted in a reduction in thermal withdrawal threshold that persisted for the 3 h tested [one-way repeated-measures (RM) ANOVA, P < 0.0001, F(3,4) = 19.30; Bonferroni's post-test, ***P < 0.001, **P < 0.01 compared with baseline]. This was unaffected by intrathecal yohimbine at 3 h following CFA (n = 5 CFA, n = 4 CFA + yoh).