Table 1.

Characteristics of the study sample according to Breslow thickness

	1.01–2.00 mm (N=123)		2.01–4.00 mm (N=83)		>4.00 mm (N=43)
	N	%	N	%	N	%	P values
Demographic Parameters
Age at diagnosis
65 years or less	83	67.5	53	63.9	22	51.2	0.160
More than 65 years	40	32.5	30	36.1	21	48.8
Sex
Male	66	53.7	46	55.4	29	67.4	0.281
Female	57	46.3	37	44.6	14	32.6
Education level
Some high school	18	14.6	14	16.9	11	25.6	0.100
High school diploma	37	30.1	19	22.9	13	30.2
Some college	22	17.9	29	34.9	8	18.6
Bachelor’s degree	23	18.7	11	13.3	7	16.3
Graduate degree	23	18.7	10	12.1	4	9.3
Marital status
Married	89	72.4	61	73.5	29	67.4	0.898
Separated/divorced	9	7.3	3	3.6	3	7.0
Widowed	12	9.8	11	13.3	6	14.0
Never married	13	10.6	8	9.6	5	11.6
Hair color
Brown or black	73	59.4	50	60.2	23	53.4	0.177
Blonde	33	26.8	14	16.9	14	32.6
Red	17	13.8	19	22.9	6	14.0
Eye color
Brown or black	26	21.1	15	18.1	8	18.6	0.847
Blue or green	97	78.9	68	81.9	35	81.4
Pathologic Parameters
Ulceration							<0.001
Absent	111	90.2	50	60.2	19	44.2
Present	12	9.8	33	39.8	24	55.8
Mitotic index
0 mitoses/mm2	13	10.6	1	1.2	0	0.0	<0.001
1–6 mitoses/mm2	92	74.8	33	39.8	19	44.2
More than 6 mitoses/mm2	18	14.6	49	59.0	24	55.8
Clark level
II–III	47	38.8	15	18.8	2	5.0	<0.001
IV–V	74	61.2	65	81.3	38	95.0
Anatomic site
Head and neck	13	10.9	15	18.8	5	11.9	0.594
Trunk	70	58.8	36	45.0	22	52.4
Upper extremities	17	14.3	14	17.5	7	16.7
Lower extremities	19	16.0	15	18.8	8	19.1
Tumor-infiltrating lymphocytes
None	57	46.3	41	49.4	20	47.6	0.327
Non-brisk	48	39.0	37	44.6	19	45.2
Brisk	18	14.6	5	6.0	3	7.1
Microsatellitosis
Absent	116	94.3	70	92.1	31	79.5	0.017
Present	7	5.7	6	7.9	8	20.5
Histologic subtype
Superficial spreading	78	64.5	36	43.9	12	28.6	<0.001
Nodular	11	9.1	23	28.1	17	40.5
Lentigo maligna	14	11.6	7	8.5	4	9.5
Other	18	14.9	16	19.5	9	21.4
Solar elastosis
Absent	87	70.7	63	75.9	33	76.7	0.618
Present	36	29.3	20	24.1	10	23.3
Regression
Absent	61	49.6	58	71.6	27	65.9	0.005
Present	62	50.4	23	28.4	14	34.2
Lifestyle Parameters
Body mass index
Less than 25 kg/m2	58	47.2	36	43.4	13	31.0	0.081
25–29.9 kg/m2	51	4.5	30	36.1	17	40.5
30 kg/m2 or more	14	11.4	17	20.5	12	28.6
Tobacco use
Never	50	42.0	31	38.8	13	31.7	0.078
Former, ≤20 pack-years	23	19.3	18	22.5	4	9.8
Former, >20 pack-years	29	24.4	22	27.5	10	24.4
Current, ≤20 pack-years	9	7.6	3	3.8	5	12.2
Current, >20 pack-years	8	6.7	6	7.5	9	22.0
Alcohol consumption
Never	29	23.6	18	21.7	14	32.6	0.222
Less than 1 drink/week	42	34.2	31	37.4	8	18.6
1–5 drinks/week	33	26.8	21	25.3	9	20.9
More than 5 drinks/week	19	15.5	13	15.7	12	27.9
Vitamin use
None	61	49.6	43	51.8	21	48.8	0.934
Any	62	50.4	40	48.2	22	51.2
Fruit consumption
Less than daily	40	32.5	30	36.1	21	48.8	0.160
Daily or more	83	67.5	53	63.9	22	51.2
Green salad consumption
Less than weekly	23	18.7	16	19.3	13	30.2	0.252
Weekly or more	100	81.3	67	80.7	30	69.8
Red meat consumption
Less than weekly	33	26.8	22	26.5	10	23.3	0.895
Weekly or more	90	73.2	61	73.5	33	76.7
Fish consumption
Less than weekly	70	56.9	55	66.3	29	67.4	0.283
Weekly or more	53	43.1	28	33.7	14	32.6

^aRows may not sum to total due to missing values; percents may not sum to 100% due to rounding