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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Cell Biochem. 2015 Jan;116(1):22–36. doi: 10.1002/jcb.24895

Fig. 2. Effect of PP2 and PP3 on the ability of TPA or a supraphysiological concentration of CCK (100 nM) to stimulate various kinases (p130CAS, Shc, p42/44, p38, JNK and GSK3-β.

Fig. 2

Rat pancreatic acinar cells and the whole cell lysates were processed as outlined in Figure 1 legend. Membranes were analyzed using anti-pY410 p130CAS, pY239/240 Shc, pY202/204 p42/44, pThr180/Y182 p38, pYThr183/Y185 JNK and pSer9 GSK3-β. Both a representative experiment of 3 others and the means of all the experiments are shown. * P< 0.05 vs control, # P< 0.05 vs PP2 alone, ∞ P< 0.05 vs PP3 alone and $ P< 0.05 comparing stimulants (CCK or TPA) vs stimulants pre-incubated with PP2 or PP3, respectively.