Rat pancreatic acinar cells were treated as indicated in the Figure 3 legend. Membranes were analyzed using anti-pY410 p130CAS, pY202/204 p42/44, pThr180/Y182 p38, pYThr183/Y185 JNK and pSer9 GSK3-β. Both a representative experiment of 3 others and the means of all the experiments are shown. * P< 0.05 vs control, # P< 0.05 vs PP2 alone, ∞ P< 0.05 vs PP3 alone and $ P< 0.05 comparing stimulants (CCK or TPA) vs stimulants pre-incubate with PP2 or PP3, respectively.