Table 1.
Intestinal microbiota composition in obese individuals
| Ref. | Subjects | Method | Firmicutes | Bacteroidetes | Actinobacteria | Proteobacteria | Archaea |
| Turnbaugh et al[30] | 12 ob/2 nw | 16 S RNA pyrosequencing 454 | + | - | / | / | / |
| Turnbaugh et al[31] | 31 MZ twin pairs/23 DZ twin pairs/46 mo | 16 S RNA pyrosequencing 454 | == | -- | ++ | == | == |
| Mouzaki et al[32] | 17 nw/11 ss/22 NASH | qPCR | ++ | -- | No statistical difference | No statistical difference | / |
| Armougom et al[33] | 20 ob/20 nw | qPCR | ++ | -- | / | / | + |
| Million et al[34] | 68 ob/47 nw | qPCR; cell counts | ++ | == | - | / | |
| Nadal et al[35] | 39 ob adolescents low calorie 10 wk | FISH | ++ | -- | ++ | ++ | ++ |
| Santacruz et al[36] | 36 ob adolescents low calorie 10 wk | RT-PCR | ++ | -- | ++ | / | / |
| Zhang et al[37] | 3 ob/3 nw | qPCR + 16 S RNA pyrosequencing 454 | +-(Lachnospiraceae) | +(Prevotellaceae) | +(Coriobacteriaceae) | + | +(Methanobrevibacter smithii) |
| Wong et al[38] | 16 ob NASH/22 nw ctrls | 16 S RNA pyrosequencing 454 | -- | ++ | -- | ++ | / |
| Zhu et al[39] | 16 nw/25 I/22 NASH | 16 S RNA pyrosequencing 454 | -- | ++ | -- | ++ | / |
| Schwiertz et al[40] | 33 ob/35 ow/30 nw | qPCR | -- | == | - | / | - |
Firmicutes: Clostridia, Lactobacillales, Coccacea; ob: Obese; nw: Normal weight; ss: Simple steatosis; ow: Overweight; MZ: Monozygotic; DZ: Dizygotic.