Table 1.
Summary of studies included in the meta-analysis
Ref. | Region | Study design | Year | Study period |
Sample size |
Level of lymphad-enectomy | Surgical extension | Reconstruction | Conversion |
Mortality |
Matched factors1 | Quality scores | ||
TLG | OG | TLG | OG | |||||||||||
Huscher et al[25] | Italy | RCT | 2005 | 1992-1996 | 30 | 29 | D1, D2 | D | B-II, R-Y | NR | 3.3% | 6.7% | - | 32 |
Pugliese et al[26] | Italy | OCS (R) | 2007 | 2000-2005 | 48 | 99 | D2 | S, T | R-Y | 2.1% | 2.1% | 3.0% | - | 7 |
Song et al[27] | South Korea | OCS (P) | 2008 | 2005-2006 | 20 | 20 | D1 + β, D2 | D | B-I, R-Y | 0 | 0 | 0 | - | 8 |
Lee et al[28] | Taiwan | OCS (P) | 2008 | 1998-2005 | 34 | 34 | D2 | S | B-II | 2.9% | 0 | 0 | 1245 | 9 |
Topal et al[29] | Belgium | OCS (R) | 2008 | 2003-2006 | 38 | 22 | D2 | T | R-Y | NR | 2.6% | 4.5% | - | 8 |
Strong et al[30] | United States | OCS (P) | 2009 | 2005-2008 | 30 | 30 | D2 | S | B-II, R-Y | NR | 0 | 0 | 1245 | 9 |
Wong et al[31] | Hong Kong | OCS (R) | 2009 | 2001-2006 | 18 | 41 | D1 + α/β, D2 | D | B-II, R-Y | 5.0% | 0 | 2.4% | - | 7 |
Chouillard et al[32] | France | OCS (P) | 2010 | 2001-2007 | 51 | 79 | D2 | D, T | B-II, R-Y | 6.0% | 0 | 2.5% | - | 9 |
Scatizzi et al[33] | Italy | OCS (P) | 2011 | 2006-2009 | 30 | 30 | D2 | D | R-Y | 6.7% | 0 | 0 | 12345 | 9 |
Moisan et al[34] | Chile | OCS (R) | 2012 | 2005-2010 | 31 | 31 | D1 + α/β, D2 | S, T | B-II, R-Y | 3.2% | 0 | 0 | 1245 | 9 |
Cianchi et al[35] | Italy | OCS (P) | 2012 | 2008-2012 | 41 | 41 | D1 + α/β, D2 | S, T | B-II, R-Y | 0 | 2.4% | 4.9% | 1245 | 8 |
Siani et al[36] | Italy | OCS (R) | 2012 | 2003-2009 | 25 | 25 | D1 + α/β, D2 | T | R-Y | 0 | 0 | 0 | 145 | 9 |
Shinohara et al[37] | Japan | OCS (P) | 2013 | 1998-2008 | 186 | 123 | D2 | D, P, T | B-I, R-Y | 2.2% | 1.1% | 0 | 12345 | 9 |
Kim et al[38] | South Korea | OCS (P) | 2013 | 2011 | 139 | 207 | D2 | T | R-Y | 0 | 0 | 0 | - | 7 |
Jadad scores;
Factors matched between groups: 1: Age; 2: Sex; 3: Body mass index; 4: Stage; 5: Type of gastrectomy. RCT: Randomized controlled trial; OCS: Observational clinical study; P: Prospectively collected data; R: Retrospectively collected data; TLG: Totally laparoscopic gastrectomy; OG: Open gastrectomy; D: Distal gastrectomy; P: Proximal gastrectomy; T: Total gastrectomy; S: Subtotal gastrectomy; B-I: Billroth-I; B-II: Billroth-II; R-Y: Roux-en-Y; NR: Not reported.