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. 2014 Sep 24;8:101. doi: 10.1186/s12918-014-0101-7

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© Wollbold et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Simulations for 500 μM TLC-S stimulation of acinar ( left ) and liver cells ( right ). A ROS burst following strong opening of mitochondrial pores causes enhanced apoptosis and decreased necrosis (cf. Figure 2).