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. 2014 Nov 13;4:7040. doi: 10.1038/srep07040

Table 2. The overall rate of nonsynonymous (dN) to synonymous (dS) substitutions and sites under positive selection in the respective protein-coding genes.

        PAML   FUBAR
       M7 vs M8  M8 vs M8a  
Gene n dN/dS (95% CI) LRT (2Δl) p-value LRT (2Δl) p-value Positively selected sites Positively selected sites
N 15 0.19 (0.13–0.28) 0.053 0.97 0.037 0.85 None None
P 6 0.49 (0.34–0.68) 1.99 0.37 1.88 0.17 None None
M 13 0.27 (0.180.39) 10.9 0.004 10.9 0.001 331, 335 335
F 19 0.17 (0.12–0.24) 0 1 0 1 None None
H 16 0.20 (0.15–0.26) 0 1 0 1 None None
L 8 0.16 (0.13–0.20) 0 1 0 1 None None

n:Number of sequences; LRT: likelihood ratio test statistic for null model versus alternative model; 2Δl: Differences in the likelihood scores of null and alternative models; Null models (Neutral model): M7 and M8a; Alternative model (Selection model): M8; Degrees of freedom for M7-M8 and M8-M8a are 2 and 1, respectively. Sites with p < 0.05 and posterior probability > 0.95 for PAML and FUBAR respectively are considered to be under positive selection. Sites that are detected to be under positive selection by both methods are in bold.