Table 2.
Line Item ABC scores dependent on soy-based formula use in autistic children.
| ABC Question | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|
| Soy N=297 |
Non-Soy N=1389 |
Mean Change | P | Soy N=44 |
Non-Soy N=217 |
Mean Change | P | |
| Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||||
| Subscale 1: Irritability | ||||||||
| 2 injures self | 0.29 (0.62) | 0.23 (0.57) | 0.06 | 0.16 | 0.32 (0.67) | 0.24 (0.54) | 0.08 | 0.43 |
| 4 aggressive toward others | 0.79 (0.89) | 0.75 (0.90) | 0.04 | 0.42 | 0.57 (0.79) | 0.67 (0.83) | −0.10 | 0.46 |
| 8 screams inappropriately | 0.89 (0.96) | 0.85 (0.96) | 0.04 | 0.51 | 0.84 (1.1) | 0.98 (0.97) | −0.14 | 0.39 |
| 10 temper tantrums/outbursts | 1.3 (0.97) | 1.2 (0.96) | 0.1 | 0.17 | 1.1 (0.93) | 1.3 (0.97) | −0.2 | 0.33 |
| 14 irritable and whiny | 0.94 (0.91) | 0.91 (0.90) | 0.03 | 0.66 | 0.95 (0.86) | 1.0 (0.89) | −0.05 | 0.57 |
| 19 yells at inappropriate times | 0.94 (0.97) | 0.89 (0.96) | 0.05 | 0.43 | 0.91 (1.0) | 0.94 (0.92) | −0.03 | 0.86 |
| 25 depressed mood | 0.35 (0.67) | 0.28 (0.61) | 0.07 | 0.10 | 0.43 (0.85) | 0.35 (0.64) | 0.08 | 0.50 |
| 29 demands must be met immediately | 1.3 (1.0) | 1.2 (1.0) | 0.1 | 0.072 | 1.2 (1.0) | 1.3 (1.0) | −0.1 | 0.88 |
| 34 cries over minor hurts | 0.93 (1.0) | 0.80 (0.94) | 0.13 | 0.030 | 1.2 (1.1) | 0.86 (0.94) | 0.34 | 0.059 |
| 36 mood changes quickly | 0.97 (0.92) | 0.87 (0.93) | 0.10 | 0.11 | 1.3 (1.1) | 1.0 (0.96) | 0.2 | 0.15 |
| 41 cries/screams inappropriately | 0.76 (0.93) | 0.72 (0.94) | 0.04 | 0.48 | 0.70 (0.95) | 0.91 (1.0) | −0.21 | 0.21 |
| 47 stamps feet/bangs objects/slams doors | 0.81 (1.0) | 0.71 (0.93) | 0.10 | 0.089 | 0.82 (1.0) | 0.72 (0.95) | 0.10 | 0.55 |
| 50 deliberately hurts him/herself | 0.28 (0.64) | 0.23 (0.58) | 0.05 | 0.22 | 0.36 (0.78) | 0.24 (0.53) | 0.12 | 0.18 |
| 52 physical violence to self | 0.22 (0.56) | 0.20 (0.54) | 0.02 | 0.48 | 0.34 (0.75) | 0.18 (0.50) | 0.16 | 0.087 |
| 57 temper outbursts if not own way | 1.5 (1.0) | 1.3 (1.0) | 0.2 | 0.077 | 1.5 (0.93) | 1.4 (1.0) | 0.1 | 0.65 |
| Subscale 2: Lethargy | ||||||||
| 3 listless, sluggish, inactive | 0.43 (0.73) | 0.35 (0.66) | 0.08 | 0.062 | 0.36 (0.78) | 0.44 (0.74) | −0.08 | 0.55 |
| 5 seeks isolation from others | 1.0 (0.86) | 1.0 (0.89) | 0 | 0.38 | 1.0 (1.0) | 1.1 (0.89) | −0.1 | 0.58 |
| 12 preoccupied, stares into space | 0.89 (0.81) | 0.88 (0.85) | 0.01 | 0.85 | 0.98 (0.90) | 0.85 (0.82) | 0.13 | 0.37 |
| 16 withdrawn, prefers solitary activities | 1.2 (0.96) | 1.1 (0.94) | 0.1 | 0.15 | 1.4 (1.1) | 1.2 (0.97) | 0.2 | 0.41 |
| 20 fixed facial expression | 0.55 (0.78) | 0.48 (0.72) | 0.07 | 0.13 | 0.52 (0.85) | 0.58 (0.80) | −0.06 | 0.69 |
| 23 does nothing but sit and watch others | 0.24 (0.52) | 0.23 (0.52) | 0.01 | 0.78 | 0.39 (0.69) | 0.24 (0.59) | 0.15 | 0.16 |
| 26 resists any form of physical contact | 0.24 (0.55) | 0.25 (0.53) | −0.01 | 0.65 | 0.36 (0.61) | 0.33 (0.62) | 0.03 | 0.75 |
| 30 isolates him/herself | 0.95 (0.84) | 0.87 (0.86) | 0.08 | 0.15 | 1.2 (0.98) | 0.94 (0.86) | 0.26 | 0.074 |
| 32 sits/stands in one position for a long time | 0.23 (0.58) | 0.24 (0.58) | −0.01 | 0.91 | 0.36 (0.87) | 0.26 (0.59) | 0.10 | 0.35 |
| 37 unresponsive to structured activities | 0.53 (0.76) | 0.52 (0.77) | 0.01 | 0.87 | 0.60 (0.93) | 0.50 (0.79) | 0.10 | 0.45 |
| 40 is difficult to reach/contact/get through to | 1.0 (0.88) | 0.95 (0.87) | 0.05 | 0.45 | 1.0 (1.0) | 0.97 (0.87) | 0.03 | 0.71 |
| 42 prefers to be alone | 1.0 (0.90) | 0.95 (0.93) | 0.05 | 0.29 | 1.4 (1.1) | 1.0 (0.94) | 0.4 | 0.030 |
| 43 does not try to communicate | 0.43 (0.81) | 0.39 (0.75) | 0.04 | 0.41 | 0.70 (0.93) | 0.47 (0.81) | 0.23 | 0.088 |
| 53 inactive, no spontaneous movement | 0.12 (0.42) | 0.10 (0.37) | 0.02 | 0.30 | 0.14 (0.63) | 0.12 (0.35) | 0.02 | 0.81 |
| 55 responds negatively to affection | 0.27 (0.59) | 0.27 (0.57) | 0 | 0.98 | 0.41 (0.66) | 0.33 (0.63) | 0.08 | 0.44 |
| 58 shows few social relations to others | 1.0 (0.92) | 0.99 (0.90) | 0.01 | 0.90 | 1.0 (0.90) | 1.1 (1.0) | −0.1 | 0.75 |
| Subscale 3: Stereotypy | ||||||||
| 6 meaningless, recurrent body movements | 0.98 (0.96) | 0.96 (0.95) | 0.02 | 0.71 | 0.84 (1.1) | 0.91 (0.99) | −0.07 | 0.66 |
| 11 stereotypical behavior | 1.1 (0.97) | 1.1 (0.98) | 0 | 0.88 | 1.2 (1.0) | 0.97 (0.98) | 0.23 | 0.20 |
| 17 odd, bizarre behavior | 0.96 (0.90) | 0.99 (0.90) | −0.03 | 0.64 | 0.98 (0.90) | 1.0 (0.92) | −0.02 | 0.76 |
| 27 move or rolls head back/forth repeatedly | 0.16 (0.48) | 0.15 (0.46) | 0.01 | 0.61 | 0.25 (0.65) | 0.12 (0.46) | 0.13 | 0.13 |
| 35 repetitive hand/body/head movements | 0.90 (0.99) | 0.91 (0.97) | −0.01 | 0.95 | 0.98 (1.0) | 0.85 (0.97) | 0.13 | 0.44 |
| 45 waves or shakes extremities repeatedly | 0.67 (0.93) | 0.62 (0.89) | 0.05 | 0.42 | 0.80 (0.90) | 0.54 (0.84) | 0.26 | 0.069 |
| 49 repeatedly rocks back and forth | 0.29 (0.65) | 0.25 (0.60) | 0.04 | 0.35 | 0.36 (0.87) | 0.26 (0.61) | 0.10 | 0.34 |
| Subscale 4: Hyperactivity | ||||||||
| 1 excessively active | 1.1 (0.99) | 1.0 (1.0) | 0.1 | 0.31 | 0.82 (0.95) | 0.90 (0.97) | −0.08 | 0.61 |
| 7 boisterous | 1.0 (0.94) | 1.0 (0.95) | 0 | 0.60 | 0.86 (1.0) | 0.82 (0.91) | 0.04 | 0.80 |
| 13 impulsive | 1.4 (1.0) | 1.3 (0.99) | 0.1 | 0.11 | 1.0 (1.0) | 1.2 (0.94) | −0.2 | 0.18 |
| 15 restless, unable to sit still | 1.3 (1.0) | 1.3 (1.0) | 0 | 0.35 | 1.1 (1.1) | 1.1 (0.99) | 0 | 0.76 |
| 18 disobedient, difficult to control | 1.0 (0.93) | 0.98 (0.96) | 0.02 | 0.62 | 0.82 (0.92) | 0.93 (0.87) | −0.11 | 0.46 |
| 21 disturbs others | 1.1 (0.91) | 1.1 (0.92) | 0 | 0.12 | 0.73 (0.85) | 0.98 (0.90) | −0.25 | 0.091 |
| 24 uncooperative | 0.81 (0.84) | 0.85 (0.85) | −0.04 | 0.44 | 0.61 (0.78) | 0.90 (0.79) | −0.29 | 0.030 |
| 28 does not pay attention to instructions | 1.3 (0.82) | 1.3 (0.86) | 0 | 0.82 | 1.3 (1.0) | 1.2 (0.81) | 0.1 | 0.84 |
| 31 disrupts group activities | 0.95 (0.95) | 0.95 (0.91) | 0 | 0.95 | 0.95 (1.0) | 0.87 (0.91) | 0.08 | 0.56 |
| 38 does not stay in seat | 1.2 (0.99) | 1.1 (1.0) | 0.1 | 0.33 | 1.1 (1.2) | 1.0 (1.0) | 0.1 | 0.71 |
| 39 will not sit still for any length of time | 0.94 (0.93) | 0.93 (0.96) | 0.01 | 0.83 | 0.82 (1.1) | 0.84 (0.95) | −0.02 | 0.88 |
| 44 easily distracted | 1.5 (0.99) | 1.5 (0.99) | 0 | 0.98 | 1.4 (1.0) | 1.4 (0.98) | 0 | 0.89 |
| 48 constantly runs or jumps | 0.96 (1.0) | 0.92 (1.0) | 0.04 | 0.53 | 0.91 (1.0) | 0.78 (1.0) | 0.13 | 0.45 |
| 51 pays no attention when spoken to | 0.96 (0.82) | 0.97 (0.79) | −0.01 | 0.87 | 0.93 (0.90) | 1.0 (0.84) | −0.07 | 0.63 |
| 54 tends to be excessively active | 1.1 (1.1) | 0.97 (1.1) | 0.13 | 0.24 | 0.91 (1.1) | 0.76 (0.98) | 0.15 | 0.38 |
| 56 deliberately ignores directions | 0.81 (0.85) | 0.74 (0.85) | 0.07 | 0.20 | 0.70 (0.95) | 0.67 (0.75) | 0.03 | 0.81 |
| Subscale 5: Inappropriate Speech | ||||||||
| 9 talks excessively | 0.86 (0.99) | 0.77 (0.94) | 0.09 | 0.13 | 0.86 (0.98) | 0.68 (0.91) | 0.18 | 0.22 |
| 22 repetitive speech | 1.1 (0.99) | 1.2 (1.0) | −0.1 | 0.12 | 1.4 (1.1) | 1.1 (0.97) | 0.3 | 0.10 |
| 33 talks to self loudly | 0.61 (0.84) | 0.65 (0.89) | −0.04 | 0.49 | 0.89 (1.0) | 0.64 (0.93) | 0.25 | 0.12 |
| 46 repeats a word or phrase over and over | 0.99 (1.1) | 1.1 (1.0) | −0.11 | 0.32 | 1.3 (1.1) | 1.0 (1.0) | 0.3 | 0.11 |