Table 3.
Genes Downregulated in the Hypothalamus by T3 Administration to Hypothyroid Rats
| Name | GeneName | Description | Average intensity | Fold change | p-Value |
|---|---|---|---|---|---|
| NM_031655 | Lxn | Rattus norvegicus latexin (Lxn), mRNA | 12.66201 | −1.35033 | 0.000648 |
| XM_001057696 | LOC680551 | PREDICTED: Rattus norvegicus similar to Apolipoprotein C-IV precursor (Apo-CIV) (ApoC-IV) (Apolipoprotein C2-linked) (ACL) (LOC680551), mRNA | 7.883503 | −1.38783 | 0.000567 |
| BG378227 | BG378227 | BG378227 UI-R-CV1-bvp-e-08-0-UI.s1 UI-R-CV1 Rattus norvegicus cDNA clone UI-R-CV1-bvp-e-08-0-UI 3′, mRNA sequence | 8.967155 | −1.41934 | 0.000535 |
| NM_001007611 | RGD1359691 | Rattus norvegicus hypothetical LOC287534 (RGD1359691), mRNA | 10.1962 | −1.43904 | 0.000486 |
| XM_001072931 | Rgc32 | PREDICTED: Rattus norvegicus response gene to complement 32 (Rgc32), mRNA | 12.76325 | −1.4407 | 0.000328 |
| XM_215897 | Acss1_predicted | PREDICTED: Rattus norvegicus acyl-CoA synthetase short-chain family member 1 (predicted) (Acss1_predicted), mRNA | 10.24754 | −1.44698 | 0.000452 |
| NM_017080 | Hsd11b1 | Rattus norvegicus hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), mRNA | 11.85208 | −1.45705 | 0.000281 |
| XM_228918 | Egfl6 | PREDICTED: Rattus norvegicus EGF-like-domain, multiple 6 (Egfl6), mRNA | 8.049509 | −1.45987 | 0.00052 |
| AJ003232 | AJ003232 | RNAJ3232 Rattus norvegicus mRNA for MHC class II RT1-D beta1 chain haplotype k | 8.027006 | −1.46109 | 0.000294 |
| NM_139185 | Gng8 | Rattus norvegicus guanine nucleotide binding protein (G protein), gamma 8 subunit (Gng8), mRNA | 11.97161 | −1.46169 | 0.000535 |
| XM_214671 | XM_214671 | Rattus norvegicus hypothetical LOC291982 (LOC291982), mRNA | 9.387132 | −1.4865 | 0.000345 |
| AW915522 | AW915522 | AW915522 EST346826 Normalized rat embryo, Bento Soares Rattus sp. cDNA clone RGICW33 5′ end, mRNA sequence | 10.68714 | −1.49131 | 0.000305 |
| NM_031853 | Dbi | Rattus norvegicus diazepam binding inhibitor (Dbi), mRNA | 15.08979 | −1.54028 | 0.000191 |
| NM_019195 | Cd47 | Rattus norvegicus CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (Cd47), mRNA | 11.3667 | −1.5486 | 0.000156 |
| NM_138530 | Mawbp | Rattus norvegicus MAWD binding protein (Mawbp), mRNA | 12.24495 | −1.58734 | 0.00021 |
| XM_237195 | LOC301444 | PREDICTED: Rattus norvegicus pseudogene for diazepam binding inhibitor 1 (LOC301444), mRNA | 9.247721 | −1.59304 | 0.000479 |
| TC525753 | TC525753 | Unknown | 7.984411 | −1.60262 | 0.00012 |
| NM_012493 | Afp | Rattus norvegicus alpha-fetoprotein (Afp), mRNA | 8.675151 | −1.61028 | 0.000542 |
| NM_144750 | LOC246266 | Rattus norvegicus lysophospholipase (LOC246266), mRNA | 9.523682 | −1.72725 | 0.000221 |
| XM_341702 | RGD1309651_predicted | PREDICTED: Rattus norvegicus similar to 1190005I06Rik protein (predicted) (RGD1309651_predicted), mRNA | 8.892309 | −1.74107 | 0.000133 |
| NM_134326 | Alb | Rattus norvegicus albumin (Alb), mRNA | 8.237368 | −1.87847 | 0.00036 |
| TC550174 | TC550174 | Unknown | 7.24582 | −1.91585 | 7.30E-05 |
| XM_001065258 | LOC683288 | PREDICTED: Rattus norvegicus similar to Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (LOC683288), mRNA | 11.71853 | −2.06669 | 0.008379 |
| NM_173123 | Cyp4f4 | Rattus norvegicus cytochrome P450, family 4, subfamily f, polypeptide 4 (Cyp4f4), mRNA | 11.15458 | −2.07395 | 0.00184 |
| XM_001057122 | LOC681501 | PREDICTED: Rattus norvegicus similar to potassium voltage-gated channel, Isk-related family, member 1-like (LOC681501), mRNA | 10.65445 | −2.21831 | 3.61E-05 |