FIG. 1.

(a) Cross-sections of hematoxilin and eosin and immunohistochemical staining for collagen type IV, early (keratin 10 [K10]) and late (filaggrin, loricrin) differentiation markers, and for desquamation-related proteins kallikrein 5 (KLK5), Lekti. (b) Graph represents the proliferation index of human skin equivalents (HSEs) and N-HSEs. (c) Graph represents the stratum corneum (SC) thickness in terms of number of SC layers. Data represent the mean+SD of four experiments. Scale bars represent 50 μm. Color images available online at www.liebertpub.com/tea