Table 1.
Mean (±SD) age at onset, death and duration of illness for groups of patients with FTD, FTD + MND or MND associated with expansions in C9ORF72 , or mutations in GRN , or not known to be associated with any known FTLD or MND associated genes
| Group | M/F | Age at onset (y) | Age at Death (y) | Duration of illness (y) |
|---|---|---|---|---|
| C9ORF72 FTD | 7/1 | 61.1 ± 8.5 | 67.6 ± 7.0 | 6.5 ± 3.0 |
| C9ORF72 FTD + MND | 2/4 | 58.8 ± 6.1 | 64.7 ± 5.8 | 5.8 ± 6.2 |
| C9ORF72 MND | 6/1 | 55.8 ± 8.6 | 57.6 ± 7.6 | 2.8 ± 1.7 |
| All C9ORF72 cases | 15/6 | 58.9 ± 7.8 | 63.4 ± 7.9 | 5.2 ± 4.1 |
| GRN FTD | 7/5 | 60.8 ± 5.9 | 69.7 ± 3.9 | 8.8 ± 3.8 |
| Non-mutational FTD | 2/2 | 60.8 ± 11.9 | 68.0 ± 15.6 | 7.3 ± 4.1 |
| Non-mutational FTD + MND | 9/1 | 59.3 ± 7.0 | 65.4 ± 8.2 | 6.2 ± 3.8 |
| All non-mutational FTD | 11/3 | 59.6 ± 12.7 | 63.4 ± 13.6 | 2.4 ± 1.1 |
| Non-mutational MND | 12/8 | 59.7 ± 8.2 | 66.1 ± 10.2 | 6.5 ± 3.8 |
FTD = Frontotemporal Dementia, FTD + MND + Frontotemporal dementia and Motor Neurone disease, MND = Motor Neurone Disease.