Table 2.
Summated scores for DPR pathology ratings in Cortical, Medial Temporal, Motor, Subcortical and Cerebellar regions, as well as total score across all 5 regions, for patients with FTD (cases #1-8), FTD + MND (cases#9-14) and MND (cases#41-47) associated with expansion in C9ORF72
| Case ID# | Summated DPR score | ||||||
|---|---|---|---|---|---|---|---|
| Pathology | Cortex | Medial temporal | Motor | Subcortical | Cerebellar | Total | |
| 1 | FTLD-TDP A | 16 | 12 | 3 | 3 | 5 | 39 |
| 2 | FTLD-TDP A | 12 | 14 | 3 | 1 | 5.5 | 35.5 |
| 3 | FTLD-TDP A | 15 | 18 | 3 | 5 | 7.5 | 48.5 |
| 4 | FTLD-TDP A | 13 | 12 | 2 | 2.5 | 3.5 | 33 |
| 5 | FTLD-TDP A | 12 | 11 | 1 | 3 | 3 | 30 |
| 6 | FTLD-TDP A | 11 | 9 | 1.5 | 3 | 2 | 26.5 |
| 7 | FTLD-TDP A | 12 | 9.5 | 1 | 5.5 | 3.5 | 31.5 |
| 8 | FTLD-TDP A | 22 | 23 | 2 | 4 | 5.5 | 55.5 |
| 9 | FTLD-TDP B | 20 | 15.5 | 2 | 1 | 4.5 | 43 |
| 10 | FTLD-TDP B | 12 | 11 | 2 | 2 | 4 | 31 |
| 11 | FTLD-TDP B | 11 | 10.5 | 2 | 1.5 | 4 | 29 |
| 12 | FTLD-TDP B | 18 | 16 | 3.5 | 4.5 | 5 | 47 |
| 13 | FTLD-TDP B | 11 | 11 | 2 | 3.5 | 2 | 29.5 |
| 14 | FTLD-TDP B | 16 | 15 | 3 | 4.5 | 6.5 | 45 |
| 41 | MND | 16 | 13 | 3 | 6 | 5.5 | 43.5 |
| 42 | MND | 15 | 13 | 3 | 3 | 1 | 35 |
| 43 | MND | 14 | 18 | 3 | 4 | 3 | 42 |
| 44 | MND | 12 | 18 | 2.5 | 5 | 3 | 40.5 |
| 45 | MND | 13 | 12 | 3 | 1.5 | 4.5 | 34 |
| 46 | MND | 11 | 19 | 2 | 4.5 | 3 | 39.5 |
| 47 | MND | 23 | 23 | 3 | 5 | 3.5 | 57.5 |