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. 2014 Jun 17;2:18. doi: 10.1186/2052-8426-2-18

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© Harraz et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Single-cell dendritic tree development analysis in ESCs-derived human neurons. (A) Sample 2D projection trajectories of the dendrites of hESCs-derived Tuj-1-positive neurons. (B) Cumulative distribution plot of total dendrite length. (***p < 0.001, Kolmogorov-Smirnov test). (C) Cumulative distribution plot of dendrite branch number. (***p < 0.001, Kolmogorov-Smirnov test). (D) Sholl analysis of neurons dendrite complexity (***p < 0.001, Two way ANOVA). Data replicated 3 independent times. In each replicate; (NT) (n = 40), miR-223 (n = 40).