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Increase in XBP1 mRNA splicing and CHOP expression in diabetic retinas. mRNA expression of spliced XBP1, total XBP1, and CHOP in retinas from 6-month-old Akita mice were determined by qRT-PCR. The values were normalized by 18S ribosome RNA and expressed as mean ± S.D. (n = 7 in control group and n = 4 in Akita group). * P < 0.01 versus control.
