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. 2014 Jun 24;16(3):R67. doi: 10.1186/bcr3682

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Copyright © 2014 Vazquez-Ortiz et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Caspase 3/7 activity and cell cycle distribution of 92 J isogenic cell lines upon lestaurtinib and/or AG14361 treatment. (A, B) Percentage of caspase 3/7 activity in 92 J isogenic pair of cells after they were incubated with IC₅₀ of lestaurtinib and/or AG14361 in a time-dependent manner. (C, D) Distribution of 92 J isogenic pair of cells after they were treated with IC₅₀ of AG14361 and/or lestaurtinib per 12, 24, 36 and 48 hr. There was no difference in the results between the two isogenic cell lines. IC₅₀, 50% inhibition dose.