Table 2.

Global joint changes following articular fracture: correlation between arthritic changes, synovial inflammation and bone morphology

	Lateral synovitis score	Medial synovitis score			Lateral synovitis score	Medial synovitis score
Control limb			Fractured limb
Mankin total joint score	rs = 0.06, P = 0.68	rs = 0.19, P = 0.17	Mankin total joint score		rs = 0.10, P = 0.47	rs = 0.48, P = 0.001
Lateral Mankin score	rs = 0.16, P = 0.26	rs = 0.17, P = 0.24	Lateral Mankin score		rs = 0.06, P = 0.68	rs = 0.14, P = 0.31
Medial Mankin score	rs = -0.07, P = 0.60	rs = 0.10, P = 0.46	Medial Mankin score		rs = 0.16, P = 0.27	rs = 0.61, P = 0.001
	Mankin total joint score		Lateral synovitis score		Medial synovitis score
	Control limb	Fractured limb	Control limb	Fractured limb	Control limb	Fractured limb
Tibial plateau bone volume, mm3	rs = -0.30, P = 0.02	rs = -0.39, P = 0.002	rs = 0.10, P = 0.43	rs = 0.13, P = 0.32	rs = 0.11, P = 0.38	rs = -0.25, P = 0.05
Tibial Plateau bone density, mg/cm3	rs = -0.08, P = 0.55	rs = -0.29, P = 0.02	rs = 0.10, P = 0.43	rs = -0.37, P = 0.004	rs = 0.10, P = 0.46	rs = -0.48, P = 0.001
Femoral condyle cancellous bone fraction	rs = -0.07, P = 0.50	rs = -0.48, P = 0.001	rs = 0.09, P = 0.36	rs = -0.27, P = 0.006	rs = 0.16, P = 0.10	rs = -0.45, P = 0.001
Tibial metaphysis bone density, mg/cm3	rs = 0.22, P = 0.08	rs = -0.11, P = 0.40	rs = 0.13, P = 0.34	rs = -0.30, P = 0.02	rs = 0.06, P = 0.60	rs = -0.20, P = 0.12

Significant Spearman correlations, r_s, between Mankin scores of arthritic changes, synovitis scores, and bone morphology parameters following articular fracture in the knee indicate a complex interaction among joint tissues with PTA disease progression (correlation coefficients in boldface text are statistically significant, P <0.05).