Figure 3.

Locations of the telomeric breakpoints identified in the 17 atypical NF1 deletions. A schematic representation of the genes located within the region is given on top. The extent of each of the 17 atypical NF1 deletions is indicated by a red bar. The centromeric breakpoints of these deletions differ from each other and are not indicated on this schema. The numbering of the breakpoint locations is according to the human GRCh37/hg19 assembly. Five deletions exhibited breakpoints that were located within a 32.6 kb region (demarcated by a grey box). tel, telomeric direction.