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. 2014 Jul 1;5(4):81. doi: 10.1186/scrt470

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Copyright © 2014 Silva et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Concentration-dependent inhibitory effect of cardiac mesenchymal stem cells (CMSCs) on concanavalin A-stimulated splenocytes. Mouse splenocytes (SCs) were incubated for 2 days with concanavalin A in the presence of different numbers of mitomycin-treated CMSCs (CMSC/SC ratios of 1:1, 1:10, and 1:100). Spleen cell proliferation was assessed on day 3 by pulsing with ³H-thymidine for 18 hours. Values represent the mean ± standard error of the mean from four independent experiments performed in triplicate. CPM = counts per minute. ** p < 0.01, *** p < 0.001.