Skip to main content
. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001800. doi: 10.1002/14651858.CD001800.pub2
Methods Post MI randomised four weeks after discharge. 88 participants were randomised, but 13 failed to follow up. Therefore 75 took part in the study
Participants 75 men < 66 yrs with 1st MI.
Mean age
I = 52.2 (+/−7.5),
C= 55.6 (+/−6.3).
Interventions Aerobic activity e.g. running, cycling, skipping + weights for 1 hour × 2 weekly for 2 months, then × 1 week for 10 months. Then continue at home.
F/U @ 1, 13, 25, & 37 months post discharge.
Outcomes Total & CHD mortality and non fatal MI.
Notes Several participants in C trained on own initiative, but were analysed as intention to treat.
Authors concluded that PT after MI appears to reduce consequences and to improve PWC, but PWC declines once participant on their own.
PT had no effect on period of convalescence or return to work, but age and previous occupation were of significance
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Low risk “random numbers”
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding (performance bias and detection bias)
All outcomes
Unclear risk Unclear in terms of assessment of outcomes.
Incomplete outcome data (attrition bias)
All outcomes
High risk 15% lost to follow-up, no description of withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk No information reported.