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. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001800. doi: 10.1002/14651858.CD001800.pub2
Methods Single-centre open RCT in Finland
Participants N Randomised:
Total: 228 (201 males, 27 females);
EX: 119 (104 males, 15 females)
UC: 109 (97 males, 12 females)
Baseline Characteristics:
Previous unstable angina (%): EX: 29; UC: 31
Previous MI (%):EX: 42; UC: 46
Hypertension (%):EX 31;UC 23
LVEF (%):EX: 70.3 (SD 11.5); UC: 71.4 (SD 12.3)
Age (years): EX: 54.1 (SD 5.9); UC: 54.3 (SD 6.2)
Percentage male:88%
Percentage white: Not reported
Inclusion/exclusion criteria:
Inclusion: patients who underwent elective CABS
Exclusion:
any other serious disease; ?65 years of age
Interventions 4 stage rehab over 30 months starting pre CABG with meeting of physician, psychologist and OT/PT.
6-8 weeks post CABG - 3 weeks IP with group sessions with psychologist, aerobic physical activity, relaxation & group discussion.
8 months post CABG - 2 days meeting with OT, nutritionist, physician, physio.
30 months post CABG - one day with nutritionist, physician & exercise.
F/U I year & 6 years
Usual care: no further details
Outcomes Mortality, CABG, health-related quality of life: Nottingham Health Profile
Notes 5 years after CABG only 20% of participants were working, despite 90% of patients being in functional classes 1-2. Almost half of patients had retired pre CABG. Many other factors affect RTW post CABG - age, education, physical requirements of the job, type of occupation, self employed status, non work income, personality type, self perception of working capacity and mostly length of absence from work pre CABG
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported.
Allocation concealment (selection bias) Unclear risk Not reported.
Blinding (performance bias and detection bias)
All outcomes
High risk “open randomised trial”
Data on deaths &admissions from the hospital records department
Incomplete outcome data (attrition bias)
All outcomes
High risk 13% lost to follow up, no description of withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk No information reported.