Methods | Prospecitve, single centre RCT in the US. F/U 6 months. | |
Participants | N= 88 (EX n=41; CON n=47) 100% male Mean age: EX= 62 +/−8, CON = 63 +/−7; (range 42 - 72) Diagnosis: CAD and a physical disability Ethnicity: NR Inclusion: ≤73 years; CAD and physical disability. CAD documented by history of MI, coronary artery bypass surgery, percutaneous transluminal coronary angioplasty or angiographically demonstrated CAD; have the functional use ofmore than 2 extremities, 1 being an arm, in order to perform the exercise test and training protocols Exclusion: uncontrolled hypertension or diabetes mellitus, clinically significant cardiac dysrhythmias, unstable angina pectoris, cognitive deficits, or other problems that would interfere with compliance to the prescribed exercise and diet protocol |
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Interventions | Exercise group (Home exercise training programme): Duration: 6 months; Frequency: 5 days/week; Session duration: 20mins/day; Intensity: 85% of predicted maximal heart rate Mode: stationary wheelchair ergometer Control group: routine care |
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Outcomes | Total mortality, non fatal MI at 6 months | |
Notes | The treatment programme decreased myocardial oxygen demand. | |
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | “randomized” |
Allocation concealment (selection bias) | Unclear risk | Not reported. |
Blinding (performance bias and detection bias) All outcomes |
Low risk | “The same experienced cardiologist interpreted all echocardiograms and was unaware of randomization procedures” |
Incomplete outcome data (attrition bias) All outcomes |
High risk | 32% lost to follow up, no description of withdrawals or dropouts |
Selective reporting (reporting bias) | Unclear risk | No information reported. |