Methods	Parallel single centre RCT in Italy; 6 month F/U
Participants	N=61 (EX n=30; CON n=31) 72.1% male. Mean age: EX=55.9 years; CON=55.1 years Diagnosis: post-infarction Ethnicity: NR Inclusion: acute ST elevation MI Exclusion: residual myocardial ischemia, severe ventricular arrhythmias, AV block, valvular disease requiring surgery, pericarditis, severe renal dysfunction (creatinine >2.5 mg/dL)
Interventions	Exercise group: Duration: 6 month; Frequency: 3×/week; Session duration: 30 min; Mode: bicycle ergometer; Intensity: target of60-70% ofVo2 peak achieved at the initial symptom-limited cardiopulmonary exercise test Control group: discharged with generic instructions to maintaining physical activity and a correct lifestyle
Outcomes	Fatal/non-fatal MI (6month F/U)
Notes
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	“randomized”
Allocation concealment (selection bias)	Unclear risk	Not reported.
Blinding (performance bias and detection bias) All outcomes	Unclear risk	The physician performing all Doppler-echocardiography and cardiopulmonary exercise tests was unaware of the results of blood sampling and was blinded to the patient allocation into the study protocol Unclear in terms of assessment of outcomes.
Incomplete outcome data (attrition bias) All outcomes	Low risk	All patients were accounted for.
Selective reporting (reporting bias)	Unclear risk	No information reported.