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. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001800. doi: 10.1002/14651858.CD001800.pub2
Methods Single centre RCT in Sweden; F/U 1 yr
Participants N= 69 (EX n=34; CON n=35)
Gender: 67 men & 2 women
Mean age 55, range 38 - 63 years
Diagnosis: Post-MI
Inclusion: Acute MI patients under 65 years of age
Exclusion: Not stated by patients have been excluded for being incapable of performing strenuous training due to poor left ventricular function or arrhythmias, orthopaedic disorders, other incapacitating somatic diseases or mental disorders
Interventions Exercise group: Duration: 12 weeks starting 8 weeks post MI.; Frequency: 2× per week; Session duration and mode: at least 45 mins (bicycling 10 mins, callisthenics 10min, jogging 15 min, relaxation 10min); Intensity: 70% to 85% of peak heart rate at the bicycle test for initial session and workload individually adjusted to obtain the desired maximum heart rate if possible
Control group: not enrolled in the training programme
Outcomes Total mortality, non-fatal MI & revascularisation.
health-related quality of life: Self report questionnaire.
Evaluations at 6 weeks and 1 year post MI
Notes Authors found no benefit from exercise training. Outcomes were related to self-rated levels of physical and psychological well being
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Low risk “Randomization was performed according to random numbers in sealed envelopes”
Allocation concealment (selection bias) Low risk “Randomization was performed according to random numbers in sealed envelopes”
Blinding (performance bias and detection bias)
All outcomes
Unclear risk Unclear in terms of assessment of outcomes.
Incomplete outcome data (attrition bias)
All outcomes
High risk 14.5% lost to follow up, no description of withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk No information reported.