Methods | Single centre RCT in Sweden; F/U 1 yr | |
Participants | N= 69 (EX n=34; CON n=35) Gender: 67 men & 2 women Mean age 55, range 38 - 63 years Diagnosis: Post-MI Inclusion: Acute MI patients under 65 years of age Exclusion: Not stated by patients have been excluded for being incapable of performing strenuous training due to poor left ventricular function or arrhythmias, orthopaedic disorders, other incapacitating somatic diseases or mental disorders |
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Interventions | Exercise group: Duration: 12 weeks starting 8 weeks post MI.; Frequency: 2× per week; Session duration and mode: at least 45 mins (bicycling 10 mins, callisthenics 10min, jogging 15 min, relaxation 10min); Intensity: 70% to 85% of peak heart rate at the bicycle test for initial session and workload individually adjusted to obtain the desired maximum heart rate if possible Control group: not enrolled in the training programme |
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Outcomes | Total mortality, non-fatal MI & revascularisation. health-related quality of life: Self report questionnaire. Evaluations at 6 weeks and 1 year post MI |
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Notes | Authors found no benefit from exercise training. Outcomes were related to self-rated levels of physical and psychological well being | |
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | “Randomization was performed according to random numbers in sealed envelopes” |
Allocation concealment (selection bias) | Low risk | “Randomization was performed according to random numbers in sealed envelopes” |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk | Unclear in terms of assessment of outcomes. |
Incomplete outcome data (attrition bias) All outcomes |
High risk | 14.5% lost to follow up, no description of withdrawals or dropouts |
Selective reporting (reporting bias) | Unclear risk | No information reported. |