Methods | Randomised 3 weeks post MI | |
Participants | 198 men < 70 yrs with MI. Mean age 52 +/−9. |
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Interventions | Patients divided into 5 interventions; 1a-extended home 1b-brief home 2a-extended group 2b-brief group 3-ETT but no further training 4-no ETT or training. |
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Home; detailed instructions + HR monitors. If free of ETT induced angina @3 weeks pts used stationary bikes for 30 mins/day, 5 days/week. If had ETT induced angina @ 3 weeks, brisk walking programme for 100 mins/week. 2× weekly telemetry to base from HR monitors. Brief intervention trained for 8 weeks, extended intervention for 23 weeks. Group intervention trained in a group with clinical supervision for 8 or 23 weeks for 3 × 1 hour/week with 100 mins/week at training rate All pts in 1a & b, 2 a & b and 3 received counselling from a physician (30-45 mins) and nurse (30-45 mins). F/U 23 weeks. |
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Outcomes | CHD mortality, non fatal MI and revascularisation | |
Notes | Low rate of cardiac events reflects identification of low risk population. Group 3 were unexpectedly active, th authors concluding that ETT + good explanation may enhance physical activity in the early stages |
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Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not reported. |
Allocation concealment (selection bias) | Unclear risk | Not reported. |
Blinding (performance bias and detection bias) All outcomes |
Unclear risk | Unclear in terms of assessment of outcomes. |
Incomplete outcome data (attrition bias) All outcomes |
High risk | 5% lost to follow up, no description of withdrawals or dropouts |
Selective reporting (reporting bias) | Unclear risk | No information reported. |