Skip to main content
. Author manuscript; available in PMC: 2014 Nov 13.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jul 6;(7):CD001800. doi: 10.1002/14651858.CD001800.pub2
Methods Participants randomised after routine angiography for angina. 66% study population had previous MI.
All participants spent one week as inpatient on a metabolic ward receiving instruction on exercise and diet
Participants 113 men with CAD, aged 35 - 68 yrs (mean 53.5)
Interventions 2 further weeks as IP, then daily exercise at home on cycle (30 mins at 75% HR max) + 2 group training sessions of 60 mins/week. Informative session held 5 times/year for participants and spouses.
F/U yearly for 6 years.
Outcomes Total and CHD mortality, non fatal MI, revascularisation,
Notes Exercise adherence in the first year was 68% (39-92%, over the next 5 years 33% (389%).
Pts with regression of coronary atheroma attended exercise sessions significantly more often (54+/− 24%) than patients with no change (20+/− 24%) or progression 31+/− 20%)
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not reported.
Allocation concealment (selection bias) Low risk “sealed envelopes”
Blinding (performance bias and detection bias)
All outcomes
Unclear risk Unclear in terms of assessment of outcomes.
Incomplete outcome data (attrition bias)
All outcomes
High risk 20% lost to follow up, no description of withdrawals or dropouts
Selective reporting (reporting bias) Unclear risk No information reported.