Methods	24 centre, pan European study conducted between 1973 and 1978. Randomised on discharge from hospital. 12 centres accepted for meta analysis
Participants	160 Men < 65 yrs with first or consecutive MI. Mean age for all participants I = 52.3, C= 53.5.
Interventions	Comprehensive programme dependent on local provision. Physical training was not compulsory but was strongly recommended. F/U 3 years Local training for 6 weeks
Outcomes	Total mortality, CVD, CHD & sudden death. Fatal & non fatal re-infarction.
Notes	Methodological problems with the execution of the study allowed only death and rein-farction to be successfully used as endpoints
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Individually randomised, but method unclear.
Allocation concealment (selection bias)	Unclear risk	Not reported.
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Unclear in terms of assessment of outcomes.
Incomplete outcome data (attrition bias) All outcomes	High risk	No description of withdrawals or dropouts. Varied greatly from site to site
Selective reporting (reporting bias)	Unclear risk	No information reported.